Serum Katak Muda Berekor Dapat Menghambat Aktivitas Proliferasi Sel Kanker

MEPNews.id- Kanker merupakan salah satu penyakit utama yang menyebabkan kematian di dunia. Di Indonesia sendiri diperkirakan angka kejadian akibat penyakit itu terdapat sekitar 100 orang dalam 100.000 penduduk. Berdasarkan fakta tersebut kelompok Program Kreativitas Mahasiswa bidang Penelitian Eksakta (PKM-PE) dari Fakultas Kedokteran Hewan (FKH) Universitas Airlangga melakukan penelitian tentang kanker.

Hasil penelitian yang dilakukan bahwa pemberian serum katak muda berekor dapat menurunkan aktifitas sel kanker. Hal ini karena di dalam serum katak muda berekor mengandung hormon tiroksin. Hormon ini berperan penting dalam mendegenerasi ekor katak yang merupakan proses apoptosis.

ai???Berawal dari hal inilah tim kami mengajukan proposal dan berhasil lolos dari penilaian Dikti untuk mendapat pendanaan dari Kemenristekdikti dan penelitian ini bisa dilakukan,ai??? kata Imas Hapsari Rahmaningtyas, ketua tim peneliti mahasiswa ini, didampingi keempat temannya yaitu Nur Prabowo Dwi Cahyo, Zeni Prastika, Arliandra Reza Pratama, dan Anjani Marisa Kartikasari.

Penelitian yang dilakukan Imas Dkk ini sekitar tiga minggu di laboratorium kampus Universitas Airlangga dengan menginduksikan reagen kanker, yaitu DMBA (Dimetylbenz (Ii??) Antrasen) http://mitupo.org/buying-cannabis-seeds-legal-in-uk ke hewan coba yaitu tikus putih jenis Sprague Dawley. Selama sekitar dua minggu dengan intensitas seminggu dua kali, setiap hari Senin dan Kamis.

Setelah menginduksikan kanker, penelitian dilanjutkan dengan memberikan serum katak muda berekor pada mencit setiap hari selama satu minggu. Dari penelitian ini diperoleh hasil bahwa serum katak muda berekor dapat menghambat aktivitas proliferasi sel kanker kulit.

Hal tersebut dibuktikan setelah dilakukan uji Imunohistokimia, yang hasilnya menunjukkan adanya warna cokelat yang menandakan adanya apoptosis. Adanya warna cokelat tersebut karena diwarnai oleh Caspase http://ycecea.hk/?p=9092 http://flyingfoxusa.com/?p=11268 3 sehingga terlihat warna cokelat. Dari hasil itu sekaligus menunjukkan bahwa serum yang diberikan dapat meningkatkan apoptosis dan menghambat aktivitas proliferasi dari sel kanker.

ai???Kami berharap dengan adanya temuan serum ini bisa memberikan alternatif atau cara terbaru dalam mengatasi kanker dengan biaya yang lebih murah daripada dilakukan dengan operasi dan nanoteknologi,ai??? kata Imas Hapsari Rahmaningtyas. 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